Bringing Gene Therapies for HIV Illness to Useful resource-Restricted Components of the World
Even if 59% of individuals dwelling with HIV (PLHIV) at the moment obtain viral suppression on antiretroviral remedy (ART), current features in controlling the worldwide HIV/AIDS epidemic could also be threatened: key HIV incidence charges are declining solely modestly, the sustainability of packages to develop ART stays unclear, and the “youth bulge” in sub-Saharan Africa contributes to a rising at-risk inhabitants.1 Though a lot effort has been dedicated to prevention interventions, these face main technical and/or implementation challenges. A complementary method is a protected, efficient, and sturdy intervention that utterly eliminates HIV an infection (“eradication”) or that suppresses viremia within the absence of ART (“remission”) (each of those states are known as an “HIV remedy” herein).
Although a frightening aim, the scientific foundation is evident: long-term remission if not eradication has been noticed within the “Berlin affected person”2 in addition to the “London affected person”three following transplantation of bone marrow progenitor cells missing the viral co-receptor, CCR5; and sturdy remission happens in tens of hundreds of PLHIV (so-called “Elite Controllers”), a few of whom (“Distinctive Elite Controllers”) might have eradicated their infections by pure immunity.4,5 Ongoing work over the previous decade means that HIV remedy may be induced by some interventions, alone or together, together with provision of broadly neutralizing antibodies (bNAbs), era of efficient antiviral CD8+ T cell responses, and knock-out of the viral co-receptor, CCR5.6
Little is thought, nonetheless, concerning the nature and vulnerabilities of the rebound-competent viral reservoir that persists regardless of ART and concerning the immunologic management of virus within the absence of ART; right now’s “greatest bets,” in different phrases, should nonetheless be seen as lengthy photographs. Initiated by the Invoice & Melinda Gates Basis in 2019, the HIV Frontiers Program goals to maneuver work on HIV remedy in the direction of interventions that may finally be obtainable to all, most particularly these in resource-limited components of the world the place the prevalence of illness is excessive (Determine 1). It begins with the premise that the journey can be lengthy (15-25 years) and that it’ll finally yield a “single-shot remedy,” i.e., a product that’s delivered percutaneously (“in vivo”) in a single encounter, safely and successfully modifying chosen cells within the physique in order that viral replication and unfold are suppressed and re-infection blocked.
This aspirational aim is prone to be realized by a sequence of progressive interventions that transfer from mixture therapies supplied over an extended length of time to these wherein cells are modified outdoors of the physique (“ex vivo”) previous to re-infusion.7 The work will construct on present information to advance by a sequence of technical and sensible hurdles whereas additionally gathering new information to greatest design a healing intervention for HIV and to find out whether or not and the way it may be used.
To get to the purpose of getting a “single-shot remedy” for HIV in hand, two interlocking areas of focus are being pursued: Present Greatest Bets: To attenuate the anticipated time to impression, investments are being made in all the crucial components of a “single-shot” HIV remedy in parallel. As a important enabler, the Program is leveraging the appreciable curiosity and sources in biotech/pharma corporations that at the moment are creating ex vivo genetic and cell-based interventions; uniquely amongst ongoing efforts, it intends to shift the emphasis of such interventions to supply in vivo, an method that’s more likely to profit these in resource-limited components of the world.
Early types of the “single-shot” remedy would faucet present “greatest bets” (i.e., administration of two or extra bNAbs, induction of a sturdy T cell response towards HIV, and CCR5 knock-out), rapidly pivoting to others ought to they come up, and asking the questions: can these interventions be delivered effectively and safely to acceptable cell populations in vivo; if that’s the case, can they be related to strategies to detect their failure; and, importantly, is there a viable pathway for product growth and distribution in sub-Saharan Africa? Incremental steps are being taken to maximise the chance of success, with growth and validation of novel approaches for concentrating on and enhancing chosen populations of cells (e.g., hematopoietic stem cells, CD4+ T stem central reminiscence cells, and B cells) in vivo.
Keratocan (KERA) Antibody |
abx026920-400ul |
Abbexa |
400 ul |
EUR 627.6 |
|
Keratocan (KERA) Antibody |
abx026920-80l |
Abbexa |
80 µl |
EUR 343.2 |
|
Keratocan (KERA) Antibody |
20-abx129874 |
Abbexa |
-
EUR 526.80
-
EUR 159.60
-
EUR 1479.60
-
EUR 710.40
-
EUR 393.60
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Keratocan (KERA) Antibody |
20-abx321066 |
Abbexa |
|
|
|
Cow Keratocan (KERA) Protein |
20-abx166318 |
Abbexa |
-
EUR 895.20
-
EUR 360.00
-
EUR 2815.20
-
EUR 1078.80
-
EUR 644.40
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Keratocan Antibody / KERA |
F54366-0.08ML |
NSJ Bioreagents |
0.08 ml |
EUR 140.25 |
Description: The protein encoded by this gene is a keratan sulfate proteoglycan that is involved in corneal transparency. Defects in this gene are a cause of autosomal recessive cornea plana 2 (CNA2). |
Keratocan Antibody / KERA |
F54366-0.4ML |
NSJ Bioreagents |
0.4 ml |
EUR 322.15 |
Description: The protein encoded by this gene is a keratan sulfate proteoglycan that is involved in corneal transparency. Defects in this gene are a cause of autosomal recessive cornea plana 2 (CNA2). |
Human Keratocan (KERA) ELISA Kit |
20-abx152122 |
Abbexa |
-
EUR 8853.60
-
EUR 4719.60
-
EUR 1093.20
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
Human Keratocan (KERA) ELISA Kit |
abx252686-96tests |
Abbexa |
96 tests |
EUR 848.4 |
|
Mouse Keratocan (KERA) ELISA Kit |
abx389686-96tests |
Abbexa |
96 tests |
EUR 1093.2 |
|
Sheep Keratocan (KERA) ELISA Kit |
abx355357-96tests |
Abbexa |
96 tests |
EUR 1111.2 |
|
Human Keratocan (KERA) ELISA Kit |
DLR-KERA-Hu-48T |
DL Develop |
48T |
EUR 620.4 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Keratocan (KERA) in samples from tissue homogenates, cell lysates or other biological fluids. |
Human Keratocan (KERA) ELISA Kit |
DLR-KERA-Hu-96T |
DL Develop |
96T |
EUR 807.6 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Keratocan (KERA) in samples from tissue homogenates, cell lysates or other biological fluids. |
CLIA kit for Human KERA (Keratocan) |
E-CL-H1116 |
Elabscience Biotech |
1 plate of 96 wells |
EUR 700.8 |
|
Description: A sandwich CLIA kit for quantitative measurement of Human KERA (Keratocan) in samples from Serum, Plasma, Cell supernatant |
Human KERA(Keratocan) ELISA Kit |
EH3283 |
FN Test |
96T |
EUR 628.92 |
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
Human Keratocan (KERA) ELISA Kit |
SEC553Hu-10x96wellstestplate |
Cloud-Clone |
10x96-wells test plate |
EUR 5677.8 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Keratocan (KERA) in tissue homogenates, cell lysates and other biological fluids. |
Human Keratocan (KERA) ELISA Kit |
SEC553Hu-1x48wellstestplate |
Cloud-Clone |
1x48-wells test plate |
EUR 572.76 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Keratocan (KERA) in tissue homogenates, cell lysates and other biological fluids. |
Human Keratocan (KERA) ELISA Kit |
SEC553Hu-1x96wellstestplate |
Cloud-Clone |
1x96-wells test plate |
EUR 766.8 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Keratocan (KERA) in tissue homogenates, cell lysates and other biological fluids. |
Human Keratocan (KERA) ELISA Kit |
SEC553Hu-5x96wellstestplate |
Cloud-Clone |
5x96-wells test plate |
EUR 3090.6 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Keratocan (KERA) in tissue homogenates, cell lysates and other biological fluids. |
Human Keratocan (KERA) ELISA Kit |
4-SEC553Hu |
Cloud-Clone |
-
EUR 5738.40
-
EUR 3031.20
-
EUR 768.00
|
- 10 plates of 96 wells
- 5 plates of 96 wells
- 1 plate of 96 wells
|
|
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Keratocan (KERA) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. |
Human Keratocan ELISA Kit (KERA) |
RK01722 |
Abclonal |
96 Tests |
EUR 625.2 |
Human Keratocan (KERA) ELISA Kit |
RDR-KERA-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 652.8 |
Human Keratocan (KERA) ELISA Kit |
RDR-KERA-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 907.2 |
Human Keratocan (KERA) ELISA Kit |
RD-KERA-Hu-48T |
Reddot Biotech |
48T |
EUR 452.7 |
|
Description: tissue homogenates, cell lysates and other biological fluids. |
Human Keratocan (KERA) ELISA Kit |
RD-KERA-Hu-96T |
Reddot Biotech |
96T |
EUR 646.7 |
|
Description: tissue homogenates, cell lysates and other biological fluids. |
Human Keratocan (KERA) ELISA Kit |
AE36999HU-48Tests |
Abebio |
48 Tests |
EUR 325 |
|
Description: Human (Homo sapiens) |
Human Keratocan (KERA) ELISA Kit |
AE36999HU-96Tests |
Abebio |
96 Tests |
EUR 610 |
|
Description: Human (Homo sapiens) |
Human KERA(Keratocan) ELISA Kit |
ELK3438-48T |
ELK Biotech |
48T |
Ask for price |
|
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human KERA. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human KERA. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human KERA, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human KERA in the samples is then determined by comparing the OD of the samples to the standard curve. |
Human KERA(Keratocan) ELISA Kit |
ELK3438-96T |
ELK Biotech |
96T |
Ask for price |
|
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human KERA. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human KERA. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human KERA, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human KERA in the samples is then determined by comparing the OD of the samples to the standard curve. |
Human Keratocan (KERA) ELISA Kit |
RD-KERA-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 625.2 |
Human Keratocan (KERA) ELISA Kit |
RD-KERA-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 867.6 |
Human Keratocan (KERA) ELISA Kit |
RDR-KERA-Hu-48T |
Reddot Biotech |
48T |
EUR 475.34 |
|
Description: tissue homogenates, cell lysates and other biological fluids. |
Human Keratocan (KERA) ELISA Kit |
RDR-KERA-Hu-96T |
Reddot Biotech |
96T |
EUR 679.04 |
|
Description: tissue homogenates, cell lysates and other biological fluids. |
Human Keratocan (KERA) ELISA Kit |
DL-KERA-Hu |
DL Develop |
96T |
EUR 441 |
|
Description: tissue homogenates, cell lysates or other biological fluids. |
Human Keratocan (KERA) ELISA Kit |
DLR-KERA-Hu |
DL Develop |
96T |
EUR 463 |
|
Description: tissue homogenates, cell lysates or other biological fluids. |
Human Keratocan (KERA) ELISA Kit |
EK10230 |
SAB |
96Т |
EUR 799 |
|
Human KERA(Keratocan) ELISA Kit |
RE2047H-48wells |
Reed Biotech |
48 wells |
EUR 116.55 |
|
Human KERA(Keratocan) ELISA Kit |
RE2047H-96wells |
Reed Biotech |
96 wells |
EUR 161.55 |
|
Human Keratocytes |
ABC-TC3663 |
AcceGen |
1 vial |
Ask for price |
|
Description: The keratocyte, or corneal fibroblast, is a highly specialized cell that is sandwiched between orthogonally arranged layers of collagen lamellae in the corneal stroma. They play a key role in maintaining the structure and transparency of the cornea as they are the source of stromal collagen and proglycans. They also play important roles in corneal wound healing and tissue repair and are known to undergo phenotypic transformations in wounds due to the influence of growth factors and cytokines. Under normal conditions, the keratocyte in the adult cornea is a relatively quiescent cell. However, in the event of a corneal injury or trauma, the keratocytes differentiate into active, synthesizing cells and rapidly replace damaged stromal matrix. Cultured human keratocytes express functional IL-4Rs and IL-17R on cell surface, suggesting that these cells may contribute to the role of IL-4 and IL-17 as mediators of allergic reactions in the cornea. Changes in gene expression were reproducibly observed on keratocytes after interleukin-1 treatment which provides important insight in gene expression and suggests novel therapeutic targets for the control of corneal inflammation.HK from Gentaur Research Laboratories are isolated from human cornea. HK are cryopreserved at primary culture. Each vial contains 5×10^5 cells in 1 ml volume. HK are characterized by their spindle morphology and immunofluorescent method with antibody to fibronectin. HK are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HK are guaranteed to further expand for 15 population doublings at the condition provided by Gentaur Research Laboratories. |
Mouse Keratocan (KERa) Protein |
20-abx167289 |
Abbexa |
-
EUR 811.20
-
EUR 343.20
-
EUR 2498.40
-
EUR 961.20
-
EUR 577.20
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Human Keratocan (KERA) Protein |
20-abx654110 |
Abbexa |
-
EUR 693.60
-
EUR 309.60
-
EUR 2064.00
-
EUR 828.00
-
EUR 510.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Rabbit Keratocan (KERA) ELISA Kit |
abx355269-96tests |
Abbexa |
96 tests |
EUR 990 |
|
Monkey Keratocan (KERA) ELISA Kit |
abx354947-96tests |
Abbexa |
96 tests |
EUR 990 |
|
ELISA kit for Human KERA (Keratocan) |
E-EL-H1794 |
Elabscience Biotech |
1 plate of 96 wells |
EUR 640.8 |
|
Description: A sandwich ELISA kit for quantitative measurement of Human KERA (Keratocan) in samples from Serum, Plasma, Cell supernatant |
ELISA kit for Human Keratocan (KERA) |
KTE61923-48T |
Abbkine |
48T |
EUR 398.4 |
|
Description: Quantitative sandwich ELISA for measuring Human Keratocan (KERA) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human Keratocan (KERA) |
KTE61923-5platesof96wells |
Abbkine |
5 plates of 96 wells |
EUR 2538 |
|
Description: Quantitative sandwich ELISA for measuring Human Keratocan (KERA) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human Keratocan (KERA) |
KTE61923-96T |
Abbkine |
96T |
EUR 646.8 |
|
Description: Quantitative sandwich ELISA for measuring Human Keratocan (KERA) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human KERA (Keratocan) |
ELK3438 |
ELK Biotech |
1 plate of 96 wells |
EUR 518.4 |
|
Description: A sandwich ELISA kit for detection of Keratocan from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
Ktcn Antibody / Kera / Keratocan |
RQ7006 |
NSJ Bioreagents |
100 ug |
EUR 356.15 |
Description: Keratocan (KTN) also known as keratan sulfate proteoglycan keratocan, is a protein that in humans is encoded by the KERA gene. The protein encoded by this gene is a keratan sulfate proteoglycan that is involved in corneal transparency. Defects in this gene are a cause of autosomal recessive cornea plana 2 (CNA2). |
Keratocan Antibody |
R31830 |
NSJ Bioreagents |
100 ug |
EUR 356.15 |
Description: Keratocan (KTN), also known as keratan sulfate proteoglycan keratocan, is a protein that in humans is encoded by the KERA gene. It is mapped to 12q22. The protein encoded by this gene is a keratan sulfate proteoglycan that is involved in corneal transparency. Defects in this gene are a cause of autosomal recessive cornea plana 2 (CNA2). Keratan sulfate proteoglycans (KSPGs) are members of the small leucine-rich proteoglycan (SLRP) family. KSPGs, particularly keratocan, lumican and mimecan, are important to the transparency of the cornea. |
Chicken Keratocan (KERA) ELISA Kit |
abx354671-96tests |
Abbexa |
96 tests |
EUR 990 |
|
Recombinant Keratocan (KERA) |
4-RPC553Bo01 |
Cloud-Clone |
-
EUR 646.85
-
EUR 296.40
-
EUR 2095.68
-
EUR 778.56
-
EUR 1437.12
-
EUR 508.80
-
EUR 5059.20
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Bovine Keratocan expressed in: E.coli |
Recombinant Keratocan (KERa) |
4-RPC553Mu01 |
Cloud-Clone |
-
EUR 582.34
-
EUR 279.60
-
EUR 1853.76
-
EUR 697.92
-
EUR 1275.84
-
EUR 465.60
-
EUR 4454.40
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Mouse Keratocan expressed in: E.coli |
Recombinant Keratocan (KERA) |
RPC553Bo01 |
Cloud-Clone |
10ug |
EUR 196 |
Recombinant Keratocan (KERA) |
RPC553Hu01 |
Cloud-Clone |
10ug |
EUR 140 |
Recombinant Keratocan (KERA) |
RPC553Mu01 |
Cloud-Clone |
10ug |
EUR 172 |
Polyclonal Antibody to Keratocan (KERA) |
PAC553Hu01 |
Cloud-Clone |
100ul |
EUR 245 |
|
Polyclonal Antibody to Keratocan (KERA) |
PAC553Mu01 |
Cloud-Clone |
100ul |
EUR 252 |
|
Lenti ORF clone of Kera (mGFP-tagged ORF) - Rat keratocan (Kera), (10 ug) |
RR209730L4 |
Origene Technologies GmbH |
10 µg |
Ask for price |
Lenti ORF clone of Kera (Myc-DDK-tagged ORF) - Rat keratocan (Kera), (10 ug) |
RR209730L3 |
Origene Technologies GmbH |
10 µg |
Ask for price |
Keratocan (KERA) Polyclonal Antibody (Bovine) |
4-PAC553Bo01 |
Cloud-Clone |
-
EUR 331.20
-
EUR 3566.40
-
EUR 876.00
-
EUR 422.40
-
EUR 271.20
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Bovine Keratocan (KERA) |
Keratocan (KERA) Polyclonal Antibody (Bovine), PE |
4-PAC553Bo01-PE |
Cloud-Clone |
-
EUR 397.20
-
EUR 3772.80
-
EUR 1051.20
-
EUR 506.40
-
EUR 252.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Bovine Keratocan (KERA). This antibody is labeled with PE. |
Keratocan (KERA) Polyclonal Antibody (Mouse, Rat) |
4-PAC553Mu01 |
Cloud-Clone |
-
EUR 301.20
-
EUR 3091.20
-
EUR 768.00
-
EUR 379.20
-
EUR 258.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse, Rat Keratocan (KERA) |
Keratocan (KERA) Polyclonal Antibody (Mouse, Rat), PE |
4-PAC553Mu01-PE |
Cloud-Clone |
-
EUR 361.20
-
EUR 3254.40
-
EUR 921.60
-
EUR 454.80
-
EUR 236.40
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse, Rat Keratocan (KERA). This antibody is labeled with PE. |
Lenti ORF particles, Kera (GFP-tagged ORF) - Rat keratocan (Kera), 200ul, >10^7 TU/mL |
RR209730L4V |
Origene Technologies GmbH |
200 µl |
Ask for price |
Lenti ORF particles, Kera (GFP-tagged) - Mouse keratocan (Kera), 200ul, >10^7 TU/mL |
MR224411L4V |
Origene Technologies GmbH |
200 µl |
Ask for price |
Keratocan (KERA) Polyclonal Antibody (Bovine), APC |
4-PAC553Bo01-APC |
Cloud-Clone |
-
EUR 466.80
-
EUR 4686.00
-
EUR 1284.00
-
EUR 603.60
-
EUR 285.60
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Bovine Keratocan (KERA). This antibody is labeled with APC. |
Keratocan (KERA) Polyclonal Antibody (Bovine), Cy3 |
4-PAC553Bo01-Cy3 |
Cloud-Clone |
-
EUR 572.40
-
EUR 6198.00
-
EUR 1662.00
-
EUR 754.80
-
EUR 331.20
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Bovine Keratocan (KERA). This antibody is labeled with Cy3. |
Keratocan (KERA) Polyclonal Antibody (Bovine), HRP |
4-PAC553Bo01-HRP |
Cloud-Clone |
-
EUR 424.80
-
EUR 4081.20
-
EUR 1132.80
-
EUR 542.40
-
EUR 267.60
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Bovine Keratocan (KERA). This antibody is labeled with HRP. |
Keratocan (KERA) Polyclonal Antibody (Mouse, Rat), APC |
4-PAC553Mu01-APC |
Cloud-Clone |
-
EUR 421.20
-
EUR 4038.00
-
EUR 1122.00
-
EUR 538.80
-
EUR 266.40
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse, Rat Keratocan (KERA). This antibody is labeled with APC. |
Keratocan (KERA) Polyclonal Antibody (Mouse, Rat), Cy3 |
4-PAC553Mu01-Cy3 |
Cloud-Clone |
-
EUR 512.40
-
EUR 5334.00
-
EUR 1446.00
-
EUR 668.40
-
EUR 304.80
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse, Rat Keratocan (KERA). This antibody is labeled with Cy3. |
Keratocan (KERA) Polyclonal Antibody (Mouse, Rat), HRP |
4-PAC553Mu01-HRP |
Cloud-Clone |
-
EUR 385.20
-
EUR 3519.60
-
EUR 992.40
-
EUR 486.00
-
EUR 250.80
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse, Rat Keratocan (KERA). This antibody is labeled with HRP. |
Lenti ORF particles, KERA (Myc-DDK tagged) - Human keratocan (KERA), 200ul, >10^7 TU/mL |
RC207509L3V |
Origene Technologies GmbH |
200 µl |
Ask for price |
Lenti ORF particles, KERA (mGFP-tagged) - Human keratocan (KERA), 200ul, >10^7 TU/mL |
RC207509L4V |
Origene Technologies GmbH |
200 µl |
Ask for price |
Keratocan (KERA) Polyclonal Antibody (Bovine), FITC |
4-PAC553Bo01-FITC |
Cloud-Clone |
-
EUR 397.20
-
EUR 3772.80
-
EUR 1051.20
-
EUR 506.40
-
EUR 252.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Bovine Keratocan (KERA). This antibody is labeled with FITC. |
Keratocan (KERA) Polyclonal Antibody (Mouse, Rat), FITC |
4-PAC553Mu01-FITC |
Cloud-Clone |
-
EUR 361.20
-
EUR 3254.40
-
EUR 921.60
-
EUR 454.80
-
EUR 236.40
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse, Rat Keratocan (KERA). This antibody is labeled with FITC. |
Lenti ORF particles, Kera (Myc-DDK-tagged ORF) - Rat keratocan (Kera), 200ul, >10^7 TU/mL |
RR209730L3V |
Origene Technologies GmbH |
200 µl |
Ask for price |
Lenti ORF particles, Kera (Myc-DDK-tagged) - Mouse keratocan (Kera), 200ul, >10^7 TU/mL |
MR224411L3V |
Origene Technologies GmbH |
200 µl |
Ask for price |
Keratocan (KERA) Polyclonal Antibody (Bovine), APC-Cy7 |
4-PAC553Bo01-APC-Cy7 |
Cloud-Clone |
-
EUR 790.80
-
EUR 9228.00
-
EUR 2424.00
-
EUR 1063.20
-
EUR 427.20
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Bovine Keratocan (KERA). This antibody is labeled with APC-Cy7. |
Keratocan (KERA) Polyclonal Antibody (Mouse, Rat), APC-Cy7 |
4-PAC553Mu01-APC-Cy7 |
Cloud-Clone |
-
EUR 699.60
-
EUR 7932.00
-
EUR 2100.00
-
EUR 933.60
-
EUR 388.80
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse, Rat Keratocan (KERA). This antibody is labeled with APC-Cy7. |
Keratocan (KERA) Polyclonal Antibody (Bovine), Biotinylated |
4-PAC553Bo01-Biotin |
Cloud-Clone |
-
EUR 412.80
-
EUR 3506.40
-
EUR 1011.60
-
EUR 512.40
-
EUR 279.60
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Bovine Keratocan (KERA). This antibody is labeled with Biotin. |
Keratocan (KERA) Polyclonal Antibody (Mouse, Rat), Biotinylated |
4-PAC553Mu01-Biotin |
Cloud-Clone |
-
EUR 379.20
-
EUR 3031.20
-
EUR 892.80
-
EUR 464.40
-
EUR 265.20
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse, Rat Keratocan (KERA). This antibody is labeled with Biotin. |
Keratocan (KERA) (C-term) rabbit polyclonal antibody, Aff - Purified |
AP52331PU-N |
Origene Technologies GmbH |
400 µl |
Ask for price |
Human Keratocan Chemiluminescent Immunoassay Kit |
IHUKERAKTC |
Innovative research |
each |
EUR 545 |
|
Description: Human Keratocan Chemiluminescent Immunoassay Kit |
Cellufine PB |
683-986-326 |
JNC America |
50 ml |
Ask for price |
Cellufine PB |
683-986-328 |
JNC America |
500 ml |
Ask for price |
Cellufine PB |
683-986-330 |
JNC America |
5 lt |
Ask for price |
Cellufine PB |
683-986-335 |
JNC America |
10 lt |
Ask for price |
PB antibody |
70R-2192 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Rabbit polyclonal PB antibody raised against the middle region of Pb |
Pseudoproto-Pb |
TBW00844 |
ChemNorm |
unit |
Ask for price |
HighQC™ Human IPSC From Activated Fibroblast From Primary Keratocytes-Keratoconus |
ABC-SC2092 |
AcceGen |
1 vial |
Ask for price |
Description: Cell Type iPSCPrimary Tissue Activated fibroblast from primary keratocytesReprogramming Method Episomal PlasmidDisease Keratoconus; Cells are only guaranteed with purchase of Gentaur Media and Gentaur Extra Cellular Matrix for appropriate cell culture, for 30 days from the date of shipment. |
On the outset, this work is profiting from genetic “cures” for sickle cell illness that at the moment are in hand, with early outcomes indicating that substantial scientific profit may be obtained with even incomplete correction of the hemoglobin S genotype (both by enhancing the hemoglobin S allele or by upregulating hemoglobin F) in hematopoietic stem cells ex vivo.eight Profitable efforts to change hematopoietic stem cells in vivo to end in comparable corrections may kind a pathway to the in vivo introduction of modifications aimed toward HIV remedy. If profitable, the last word product can be a cheap composition that’s simply and safely delivered, and designed to impact a sturdy HIV remedy for all; en route, interventions offering profit for these with sickle cell illness (in addition to different hemoglobinopathies) ought to predictably come up.